Inégalité des sexes face au cancer en urologie [Gender disparities in urologic cancers].

Details

Serval ID
serval:BIB_F61CE55212D3
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Inégalité des sexes face au cancer en urologie [Gender disparities in urologic cancers].
Journal
Revue Médicale Suisse
Author(s)
Lucca I., Valerio M., Jichlinski P., Cerantola Y.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2015
Volume
11
Number
497
Pages
2276-8, 2280
Language
french
Notes
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Abstract
The purpose of the present review is to summarize the current knowledge on the impact of gender on urological cancers. There is a discrepancy in the incidence of urothelial and kidney cancers, with a higher prediction for male patients. Men have a three-times greater risk of developing bladder cancer compared to women, but female gender has been identified as an independent adverse prognostic factor for both disease recurrence and progression. At diagnosis, men with renal cell carcinoma present more often with larger tumors and higher stage and grade disease compared to females. Smoking habits, tumor biology, sex steroid hormones, genetic differences and social behavior may be the main drivers of gender disparities. Therefore, the inclusion of this variable in validated prognostic tables and nomograms should be concretely discussed.
Keywords
Disease Progression, Female, Health Status Disparities, Humans, Incidence, Male, Neoplasm Grading, Neoplasm Recurrence, Local, Neoplasm Staging, Prognosis, Risk Factors, Sex Factors, Urologic Neoplasms/epidemiology, Urologic Neoplasms/pathology
Pubmed
Create date
29/05/2016 12:24
Last modification date
20/08/2019 17:22
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