Autogreffe de cellules souches hématopoïétiques périphériques dans le cadre du traitement d'hémopathies malignes. Partie I: patients [Autologous transplantation of peripheral blood hematopoietic stem cells in the treatment of hematological malignancies. I: patients]

Details

Serval ID
serval:BIB_F203A020B930
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Autogreffe de cellules souches hématopoïétiques périphériques dans le cadre du traitement d'hémopathies malignes. Partie I: patients [Autologous transplantation of peripheral blood hematopoietic stem cells in the treatment of hematological malignancies. I: patients]
Journal
Schweizerische medizinische Wochenschrift
Author(s)
Medinger P., Tissot J.D., Nicoloso de Faveri G., Kovacsovics T.J., Perey L., Schneider P., Zwicky C.
ISSN
0036-7672
Publication state
Published
Issued date
04/2000
Peer-reviewed
Oui
Volume
130
Number
13
Pages
478-84
Language
french
Notes
Publication types: English Abstract ; Journal Article - Publication Status: ppublish
Abstract
61 autologous transplantations for haematological malignancies have been performed with peripheral blood stem cells in 60 patients. 26 grafts were performed for non-Hodgkin's lymphoma (18 patients were transplanted in first remission, 8 patients after progression or relapse), 13 for multiple myeloma, 7 for Hodgkin's disease and 10 for acute myeloid leukaemia. One patient died from thrombosis of the portal vein. 38 patients were in complete remission 29 months (extremes: 14-44) after transplantation. 21 of 60 patients progressed or relapsed after transplantation, and 14 died. No death was attributed to graft failure, infection or haemorrhage. In conclusion, transplantation with peripheral blood stem cells is well tolerated, has a low toxicity rate, and can be used safely for patients with haematological malignancies.
Keywords
Adolescent, Adult, Aged, Female, Follow-Up Studies, Hematologic Neoplasms/therapy, Hematopoietic Stem Cell Transplantation, Humans, Leukemia, Myeloid, Acute/blood, Lymphoma, Non-Hodgkin/blood, Male, Middle Aged, Multiple Myeloma/blood, Retrospective Studies, Transplantation, Autologous
Pubmed
Web of science
Create date
25/01/2008 16:34
Last modification date
20/08/2019 17:19
Usage data