Metastatic choroidal paraganglioma.

Details

Serval ID
serval:BIB_EF4F7BAAA873
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Metastatic choroidal paraganglioma.
Journal
Ophthalmology
Author(s)
Schalenbourg A., Moulin A., Guillou L., Zografos L.
ISSN
1549-4713 (Electronic)
ISSN-L
0161-6420
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
118
Number
11
Pages
2238-2241
Language
english
Notes
Publication types: Case Reports ; Journal Article
Abstract
PURPOSE: To describe a patient with metastatic choroidal paraganglioma that was locally controlled with radiotherapy.
DESIGN: Interventional clinicopathologic case report.
PARTICIPANT: One patient with metastatic choroidal paraganglioma.
METHODS: Interventional clinicopathologic case report and systematic search of the literature.
MAIN OUTCOME MEASURES: Description of clinicopathologic features, treatment methods, and outcome.
RESULTS: A 50-year-old man had a nonpigmented atypical choroidal mass with secondary retinal detachment in the left eye. After incisional biopsy, the diagnosis of paraganglioma was established. Metastatic work-up revealed vertebral, mediastinal, and pulmonary metastases of a nonsecretory, malignant paraganglioma without tracer uptake. The primary tumor was not identified. The ocular tumor regressed after stereotaxic radiotherapy. Two years later, recurrent lesions developed in the contralateral eye, which also was irradiated.
CONCLUSIONS: Malignant paraganglioma can metastasize in the choroid and should be included in the differential diagnosis of a nonpigmented choroidal mass. Stereotaxic radiation therapy is an effective treatment method. To the authors' knowledge, this is the first report of a patient with choroidal paraganglioma.
FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Keywords
Choroid Neoplasms/radiotherapy, Choroid Neoplasms/secondary, Humans, Lung Neoplasms/secondary, Male, Mediastinal Neoplasms/secondary, Middle Aged, Paraganglioma/radiotherapy, Paraganglioma/secondary, Spinal Neoplasms/secondary, Visual Acuity/physiology
Pubmed
Web of science
Create date
08/11/2011 10:02
Last modification date
19/03/2018 11:57
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