T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.
Details
Download: BIB_EE8EDC0ACBE8.P001.pdf (2083.25 [Ko])
State: Public
Version: author
State: Public
Version: author
Serval ID
serval:BIB_EE8EDC0ACBE8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.
Journal
Nucleic Acids Research
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2011
Volume
39
Number
Web Server issue
Pages
W13-W17
Language
english
Abstract
This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These include the default T-Coffee mode for protein and nucleic acid sequences, the M-Coffee mode that allows combining the output of any other aligners, and template-based modes of T-Coffee that deliver high accuracy alignments while using structural or homology derived templates. These three available template modes are Expresso for the alignment of protein with a known 3D-Structure, R-Coffee to align RNA sequences with conserved secondary structures and PSI-Coffee to accurately align distantly related sequences using homology extension. The new server benefits from recent improvements of the T-Coffee algorithm and can align up to 150 sequences as long as 10,000 residues and is available from both http://www.tcoffee.org and its main mirror http://tcoffee.crg.cat.
Pubmed
Open Access
Yes
Create date
05/10/2011 11:27
Last modification date
20/08/2019 17:16