Nutrition and management of glycemia in neonates with neonatal encephalopathy treated with hypothermia.

Details

Serval ID
serval:BIB_EC7B3CBFB211
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Nutrition and management of glycemia in neonates with neonatal encephalopathy treated with hypothermia.
Journal
Seminars in fetal & neonatal medicine
Author(s)
Pinchefsky E.F., Schneider J., Basu S., Tam EWY, Gale C.
Working group(s)
Newborn Brain Society Guidelines and Publications Committee*
ISSN
1878-0946 (Electronic)
ISSN-L
1744-165X
Publication state
Published
Issued date
08/2021
Peer-reviewed
Oui
Volume
26
Number
4
Pages
101268
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Adequate nutrition and glycemic homeostasis are increasingly recognized as potentially neuroprotective for the developing brain. In the context of hypoxia-ischemia, evidence is scarce regarding optimal nutritional support and administration route, as well as the short- and long-term consequences of such interventions. In this review, we summarize current knowledge on disturbances of brain metabolism of glucose and substrates by hypoxia-ischemia, and compound effects of these mechanisms on brain injury characterized by specific patterns on EEG and MRI. Risks and benefits of nutrition delivery via parenteral or enteral routes are examined. Nutrition could mitigate adverse neurodevelopmental outcomes, and the impact of nutritional strategies and specific nutritional interventions are reviewed. Limited literature highlights the need for further studies to understand the changes in energy metabolism during and after hypoxic-ischemic injury, to optimize nutritional regimens and glucose management, and to inform the neuroprotective role of nutrition.
Keywords
Brain imaging, Brain metabolism, Electroencephalogram, Hyperglycemia, Hypoglycemia, Neonatal encephalopathy, Nutrition, Parenteral nutrition
Pubmed
Web of science
Create date
02/08/2021 15:01
Last modification date
27/11/2021 7:36
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