Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes.

Details

Serval ID
serval:BIB_E9FDEA503643
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes.
Journal
Diagnostic microbiology and infectious disease
Author(s)
Poirel L., Larpin Y., Dobias J., Stephan R., Decousser J.W., Madec J.Y., Nordmann P.
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Publication state
Published
Issued date
01/2018
Peer-reviewed
Oui
Volume
90
Number
1
Pages
7-10
Language
english
Notes
Publication types: Evaluation Studies ; Journal Article
Publication Status: ppublish
Abstract
The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR-1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains either recovered from the environment, animals, or humans. Sensitivity and specificity were found to be 100%.
Keywords
Animals, Anti-Bacterial Agents/pharmacology, Colistin/pharmacology, Drug Resistance, Bacterial/genetics, Enterobacter aerogenes/drug effects, Enterobacter aerogenes/genetics, Enterobacter aerogenes/isolation & purification, Enterobacter cloacae/drug effects, Enterobacter cloacae/genetics, Enterobacter cloacae/isolation & purification, Enterobacteriaceae/drug effects, Enterobacteriaceae/genetics, Enterobacteriaceae Infections/drug therapy, Enterobacteriaceae Infections/microbiology, Escherichia coli/drug effects, Escherichia coli/genetics, Escherichia coli/isolation & purification, Escherichia coli Proteins/genetics, Humans, Klebsiella oxytoca/drug effects, Klebsiella oxytoca/genetics, Klebsiella oxytoca/isolation & purification, Klebsiella pneumoniae/drug effects, Klebsiella pneumoniae/genetics, Klebsiella pneumoniae/isolation & purification, Membrane Proteins/genetics, Microbial Sensitivity Tests, Polymyxins/pharmacology, beta-Lactamases/genetics, Enterobacteriaceae, MCR, Polymyxin, Rapid Polymyxin NP test, Resistance
Pubmed
Web of science
Create date
23/11/2017 21:20
Last modification date
20/08/2019 16:12
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