Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes.

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Serval ID
serval:BIB_E9FDEA503643
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
UNIL/CHUV
Title
Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes.
Journal
Diagnostic microbiology and infectious disease
Author(s)
Poirel L., Larpin Y., Dobias J., Stephan R., Decousser J.W., Madec J.Y., Nordmann P.
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Publication state
Published
Issued date
01/2018
Peer-reviewed
Oui
Volume
90
Number
1
Pages
7-10
Language
english
Notes
Publication types: Evaluation Studies ; Journal Article
Publication Status: ppublish
Abstract
The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR-1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains either recovered from the environment, animals, or humans. Sensitivity and specificity were found to be 100%.
Keywords
Animals, Anti-Bacterial Agents/pharmacology, Colistin/pharmacology, Drug Resistance, Bacterial/genetics, Enterobacter aerogenes/drug effects, Enterobacter aerogenes/genetics, Enterobacter aerogenes/isolation & purification, Enterobacter cloacae/drug effects, Enterobacter cloacae/genetics, Enterobacter cloacae/isolation & purification, Enterobacteriaceae/drug effects, Enterobacteriaceae/genetics, Enterobacteriaceae Infections/drug therapy, Enterobacteriaceae Infections/microbiology, Escherichia coli/drug effects, Escherichia coli/genetics, Escherichia coli/isolation & purification, Escherichia coli Proteins/genetics, Humans, Klebsiella oxytoca/drug effects, Klebsiella oxytoca/genetics, Klebsiella oxytoca/isolation & purification, Klebsiella pneumoniae/drug effects, Klebsiella pneumoniae/genetics, Klebsiella pneumoniae/isolation & purification, Membrane Proteins/genetics, Microbial Sensitivity Tests, Polymyxins/pharmacology, beta-Lactamases/genetics, Enterobacteriaceae, MCR, Polymyxin, Rapid Polymyxin NP test, Resistance
OAI-PMH
oai:serval.unil.ch:BIB_E9FDEA503643
DOI
10.1016/j.diagmicrobio.2017.09.012
Pubmed
29146285
Web of science
000418731400002
Create date
23/11/2017 22:20
Last modification date
20/08/2019 17:12
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