Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection.
Details
Serval ID
serval:BIB_E4B458967B9E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection.
Journal
Cytokine
ISSN
1096-0023 (Electronic)
ISSN-L
1043-4666
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
60
Number
2
Pages
338-340
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
Considering macrophage migratory inhibitory factor (MIF) as a critical pro-inflammatory cytokine of the immune system, we evaluated plasma MIF levels in 89 HIV-infected adults. Plasma MIF levels were higher in HIV-infected than in HIV-negative individuals. Highest MIF levels were observed during acute HIV infection (AHI) whilst patients on antiretroviral therapy (ART) had lower MIF levels, regardless of ART efficacy. Our results suggest that MIF is an integral component of the cytokine storm characteristic of AHI.
Pubmed
Web of science
Create date
20/12/2012 19:52
Last modification date
09/04/2020 6:20