Le microbiote cutané: le poids lourd sort de l'ombre [The skin microbiota: a colossus steps into the spotlight]

Details

Serval ID
serval:BIB_DAFF9A45E42A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Le microbiote cutané: le poids lourd sort de l'ombre [The skin microbiota: a colossus steps into the spotlight]
Journal
Revue medicale suisse
Author(s)
Di Domizio J., Pagnoni A., Huber M., Hohl D., Gilliet M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
30/03/2016
Peer-reviewed
Oui
Volume
12
Number
512
Pages
660-664
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
The skin contains many commensal bacteria. For years, these microbes have been considered to be exploiters of the human host for nutrients. However, recent findings indicates that the skin microbiota is also used by the human host to protect himself against invading pathogens as the commensal bacteria have direct antimicrobial capacity and provide factors required to mount a protective immune responses in the skin. While the healthy skin microbiome functions as guardians of host defense, increased or decreased bacterial composition of the skin microbiome (called dysbiosis) leads to skin inflammation and disease. Here we will review the emerging data on the role of distinct types of dysbiosis in the pathogenesis skin diseases and illustrate how the new understanding of the role of the skin microbiome has implications in the clinical management of skin diseases.
Keywords
Acne Vulgaris/microbiology, Acne Vulgaris/pathology, Dermatitis, Atopic/microbiology, Dermatitis, Atopic/pathology, Dysbiosis/microbiology, Dysbiosis/pathology, Dysbiosis/therapy, Humans, Microbiota/physiology, Psoriasis/microbiology, Psoriasis/pathology, Skin/microbiology, Skin Diseases, Infectious/microbiology, Skin Diseases, Infectious/pathology, Skin Diseases, Infectious/therapy, Symbiosis/physiology
Pubmed
Create date
14/07/2020 10:06
Last modification date
15/07/2020 6:26
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