Thromboangiitis obliterans: a rare cause of a reversible Raynaud's phenomenon.

Details

Serval ID
serval:BIB_D608CBCDAB12
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Thromboangiitis obliterans: a rare cause of a reversible Raynaud's phenomenon.
Journal
Dermatology
Author(s)
Noël B., Krayenbühl B., Cerottini J.P., Guggisberg D., Buxtorf K., Pires A., Panizzon R.G.
ISSN
1018-8665 (Print)
ISSN-L
1018-8665
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
200
Number
4
Pages
363-365
Language
english
Notes
Publication types: Case Reports ; Journal Article
Abstract
A 25-year-old woman with progressive Raynaud's phenomenon and digital necrosis is presented. Systemic sclerosis and other connective tissue disorders as well as atherosclerosis and arterial emboli were excluded with appropriate laboratory examinations. Arteriography revealed multiple palmar and digital occlusions with corkscrew-shaped vessels. Based on these characteristic arteriographic and clinical findings, the diagnosis of thromboangiitis obliterans was finally retained. With intravenous perfusion of the prostacyclin analogue iloprost (2 ng/kg/min, 6 h daily during 21 days), a complete healing of Raynaud's phenomenon and of the digital necrosis was observed. There was no recurrence during the 1-year follow-up. This observation demonstrates that thromboangiitis obliterans is a potential reversible cause of severe Raynaud's phenomenon in young women even in the absence of lower limb involvement. Early recognition is important to avoid irreversible complications such as loss of digits.
Keywords
Adult, Female, Fingers, Humans, Iloprost/therapeutic use, Raynaud Disease/drug therapy, Raynaud Disease/etiology, Skin Diseases, Vascular/drug therapy, Skin Diseases, Vascular/etiology, Thromboangiitis Obliterans/complications, Thromboangiitis Obliterans/drug therapy
Pubmed
Web of science
Create date
25/01/2008 17:54
Last modification date
20/08/2019 16:55
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