Thromboangiitis obliterans: a rare cause of a reversible Raynaud's phenomenon.

Détails

ID Serval
serval:BIB_D608CBCDAB12
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Thromboangiitis obliterans: a rare cause of a reversible Raynaud's phenomenon.
Périodique
Dermatology
Auteur(s)
Noël B., Krayenbühl B., Cerottini J.P., Guggisberg D., Buxtorf K., Pires A., Panizzon R.G.
ISSN
1018-8665 (Print)
ISSN-L
1018-8665
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
200
Numéro
4
Pages
363-365
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Résumé
A 25-year-old woman with progressive Raynaud's phenomenon and digital necrosis is presented. Systemic sclerosis and other connective tissue disorders as well as atherosclerosis and arterial emboli were excluded with appropriate laboratory examinations. Arteriography revealed multiple palmar and digital occlusions with corkscrew-shaped vessels. Based on these characteristic arteriographic and clinical findings, the diagnosis of thromboangiitis obliterans was finally retained. With intravenous perfusion of the prostacyclin analogue iloprost (2 ng/kg/min, 6 h daily during 21 days), a complete healing of Raynaud's phenomenon and of the digital necrosis was observed. There was no recurrence during the 1-year follow-up. This observation demonstrates that thromboangiitis obliterans is a potential reversible cause of severe Raynaud's phenomenon in young women even in the absence of lower limb involvement. Early recognition is important to avoid irreversible complications such as loss of digits.
Mots-clé
Adult, Female, Fingers, Humans, Iloprost/therapeutic use, Raynaud Disease/drug therapy, Raynaud Disease/etiology, Skin Diseases, Vascular/drug therapy, Skin Diseases, Vascular/etiology, Thromboangiitis Obliterans/complications, Thromboangiitis Obliterans/drug therapy
Pubmed
Web of science
Création de la notice
25/01/2008 17:54
Dernière modification de la notice
20/08/2019 16:55
Données d'usage