Evaluation of SuperCAZ/AVI® Medium for Screening Ceftazidime-avibactam Resistant Gram-negative Isolates.
Details
Serval ID
serval:BIB_CFA892B456C6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Evaluation of SuperCAZ/AVI® Medium for Screening Ceftazidime-avibactam Resistant Gram-negative Isolates.
Journal
Diagnostic microbiology and infectious disease
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Publication state
Published
Issued date
12/2021
Peer-reviewed
Oui
Volume
101
Number
4
Pages
115475
Language
english
Notes
Publication types: Evaluation Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The industrial version of SuperCAZ/AVI® medium developed for screening CAZ/AVI resistant Gram-negative isolates has been evaluated here using a collection of 87 well-characterized clinical isolates of worldwide origin. In addition, testing was performed by spiking stools with a series of resistant and susceptible isolates. In those conditions, the SuperCAZ/AVI® medium exhibited a sensitivity and specificity of 100 %, down to the lower limit of detection of 10 <sup>1</sup> to 10 <sup>2</sup> CFU/ml. The SuperCAZ/AVI® medium is a sensitive and specific screening medium for detection of CZA-resistant bacteria regardless of their resistance mechanisms.
Keywords
Anti-Bacterial Agents/pharmacology, Azabicyclo Compounds/pharmacology, Ceftazidime/pharmacology, Culture Media, Drug Combinations, Drug Resistance, Multiple, Bacterial/drug effects, Feces/microbiology, Gram-Negative Bacteria/drug effects, Gram-Negative Bacteria/isolation & purification, Gram-Negative Bacterial Infections/diagnosis, Gram-Negative Bacterial Infections/microbiology, Humans, Limit of Detection, Microbial Sensitivity Tests/instrumentation, Sensitivity and Specificity, beta-Lactamase Inhibitors/pharmacology
Pubmed
Web of science
Open Access
Yes
Create date
14/09/2021 12:37
Last modification date
10/02/2024 7:28
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