Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians.

Details

Serval ID
serval:BIB_C9BA003ED9FC
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians.
Journal
Progress in Cardiovascular Diseases
Author(s)
Stuber Thomas, Scherrer Urs
ISSN
1532-8643[electronic], 0033-0620[linking]
Publication state
Published
Issued date
2010
Volume
52
Number
6
Pages
534-539
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
About 30 million people live above 2500 m in the Andean Mountains of South America. Among them are 5.5 million Aymaras, an ethnic group with its own language, living on the altiplano of Bolivia, Peru, and northern Chile at altitudes of up to 4400 m. In this high altitude region traces of human population go back for more than 2000 years with constant evolutionary pressure on its residents for genetic adaptation to high altitude. Aymaras as the assumed direct descendents of the ancient cultures living in this region were the focus of much research interest during the last decades and several distinctive adaptation patterns to life at high altitude have been described in this ethnic group. The aim of this article was to review the physiology and pathophysiology of circulatory adaptation and maladaptation to longtime altitude exposure in Aymaras and Caucasians.
Keywords
Acclimatization, Altitude, Altitude Sickness/blood, Altitude Sickness/ethnology, Anoxia/blood, Anoxia/ethnology, Bolivia/ethnology, Cardiovascular Physiological Phenomena, Chile/ethnology, European Continental Ancestry Group, Evidence-Based Medicine, Humans, Hypertension, Pulmonary/ethnology, Indians, South American, Nitric Oxide/blood, Peru/ethnology, Polycythemia/ethnology, Pulmonary Circulation, Pulmonary Ventilation, South America/ethnology
Pubmed
Web of science
Create date
26/05/2010 13:37
Last modification date
20/08/2019 16:44
Usage data