Treatment of adult-onset Still's disease: a review

Details

Ressource 1Download: BIB_C8BCB433233B.P001.pdf (1002.46 [Ko])
State: Serval
Version: Final published version
Serval ID
serval:BIB_C8BCB433233B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Treatment of adult-onset Still's disease: a review
Journal
Therapeutics and Clinical Risk Management
Author(s)
Jamilloux Y., Gerfaud-Valentin M., Henry T., Seve P.
ISSN
1178-203X
Publication state
Published
Issued date
2015
Volume
110
Pages
33-43
Language
english
Abstract
Adult-onset Still's disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated. Indeed, there is accumulating evidence that AOSD can be divided into two distinct phenotypes based on cytokine profile, clinical presentation, and outcome, ie, a "systemic" pattern and an "articular" pattern. The first part of this review deals with the treatments that are currently available for AOSD. We then present the different strategies based on the characteristics of the disease according to clinical presentation. To do so, we focus on the two subsets of the disease. Finally, we discuss the management of life-threatening complications of AOSD, along with the therapeutic options during pregnancy.
Keywords
adult-onset Still's disease, treatment, anakinra, tocilizumab, canakinumab
Web of science
Open Access
Yes
Create date
15/01/2015 12:20
Last modification date
09/05/2019 1:10
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