Metabolomics as a Tool to Understand Pathophysiological Processes

Details

Serval ID
serval:BIB_C58D083EA586
Type
A part of a book
Publication sub-type
Chapter: chapter ou part
Collection
Publications
Institution
Title
Metabolomics as a Tool to Understand Pathophysiological Processes
Title of the book
Methods in Molecular Biology
Author(s)
Ivanisevic Julijana, Thomas Aurelien
Publisher
Springer New York
ISBN
9781493975914
9781493975921
ISSN
1064-3745
1940-6029
ISSN-L
1064-3745
Publication state
Published
Issued date
2018
Peer-reviewed
Oui
Volume
1730
Series
Methods in Molecular Biology
Chapter
1
Pages
3-28
Language
english
Abstract
Multiple diseases have a strong metabolic component, and metabolomics as a powerful phenotyping technology, in combination with orthogonal biological and clinical approaches, will undoubtedly play a determinant role in accelerating the understanding of mechanisms that underlie these complex diseases determined by a set of genetic, lifestyle, and environmental exposure factors. Here, we provide several examples of valuable findings from metabolomics-led studies in diabetes and obesity metabolism, neurodegenerative disorders, and cancer metabolism and offer a longer term vision toward personalized approach to medicine, from population-based studies to pharmacometabolomics.

Keywords
Liquid chromatography–mass spectrometry Clinical chemistry Personalized health care Precision medicine Disease markers Gas chromatography–mass spectrometry
Pubmed
Web of science
Create date
27/01/2018 12:16
Last modification date
20/08/2019 16:41
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