Les calcifications pulmonaires métastatiques [Pulmonary metastatic calcification].

Details

Serval ID
serval:BIB_C0D2FC909A84
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Les calcifications pulmonaires métastatiques [Pulmonary metastatic calcification].
Journal
Revue des Maladies Respiratoires
Author(s)
Pasquier M., Schaller M.D., Abdou M., Eckert P.
ISSN
1776-2588 (Electronic)
ISSN-L
0761-8425
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
29
Number
6
Pages
775-784
Language
french
Notes
Publication types: English Abstract ; Journal Article
Abstract
INTRODUCTION: The lung is the organ most frequently involved by metastatic calcification. This condition is probably under-diagnosed, the patients usually being asymptomatic. This article summarizes the current knowledge concerning pulmonary metastatic calcification.
BACKGROUND: The pathogenesis of pulmonary metastatic calcification is not well known, but it involves phosphate-calcium balance, renal function and pH. The most frequently encountered aetiologies are hyperparathyroidism, neoplastic bony lesions, and renal failure. The definitive diagnosis is achieved by histology, radiological examinations being insensitive. The clinical manifestations are various and can include a pulmonary restrictive syndrome, diffusion abnormalities, hypoxaemia and respiratory failure. The latter can be severe and influence the prognosis adversely: 19 cases of fatal pulmonary metastatic calcification have been reported. The treatment is aetiological and symptomatic.
VIEWPOINT: The prognostic factors for a poor outcome of this potentially lethal condition remain to be determined. The management of asymptomatic patients is also uncertain.
CONCLUSIONS: Pulmonary metastatic calcification is a rare condition of complex pathogenesis. The clinical manifestations are varied, ranging from asymptomatic to severe, even fatal.
Pubmed
Web of science
Create date
27/08/2012 17:39
Last modification date
20/08/2019 15:35
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