CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.

Details

Ressource 1Download: serval:BIB_B3A5C856592D.P001 (942.30 [Ko])
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Version: author
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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_B3A5C856592D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Journal
Cardiovascular Research
Author(s)
Mukhopadhyay P., Rajesh M., Bátkai S., Patel V., Kashiwaya Y., Liaudet L., Evgenov O.V., Mackie K., Haskó G., Pacher P.
ISSN
1755-3245[electronic], 0008-6363[linking]
Publication state
Published
Issued date
2010
Volume
85
Number
4
Pages
773-784
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't Publication
Keywords
Amidohydrolases/metabolism, Animals, Antibiotics, Antineoplastic/toxicity, Apoptosis/physiology, Cardiomyopathies/chemically induced, Cardiomyopathies/metabolism, Caspase 3/metabolism, Caspase 7/metabolism, Cells, Cultured, Cytochromes c/metabolism, Disease Models, Animal, Doxorubicin/toxicity, Endocannabinoids/metabolism, Endomyocardial Fibrosis/chemically induced, Endomyocardial Fibrosis/metabolism, Humans, MAP Kinase Signaling System/physiology, Male, Mice, Mice, Knockout, Myocytes, Cardiac/cytology, Myocytes, Cardiac/metabolism, Oxidative Stress/physiology, Poly(ADP-ribose) Polymerases/metabolism, Reactive Nitrogen Species/metabolism, Reactive Oxygen Species/metabolism, Receptor, Cannabinoid, CB1/genetics, Receptor, Cannabinoid, CB1/metabolism, Ventricular Function, Left/physiology
Pubmed
Web of science
Open Access
Yes
Create date
09/03/2011 9:20
Last modification date
25/09/2019 6:10
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