Cytological features of uterine tumors resembling ovarian sex-cord tumors in liquid-based cervical cytology: a potential pitfall. Report of a unique and rare case.

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Serval ID
serval:BIB_A6E8FDD0C508
Type
Article: article from journal or magazin.
Collection
Publications
Title
Cytological features of uterine tumors resembling ovarian sex-cord tumors in liquid-based cervical cytology: a potential pitfall. Report of a unique and rare case.
Journal
Diagnostic cytopathology
Author(s)
Dubruc E., Alvarez Flores M.T., Bernier Y., Gherasimiuc L., Ponti A., Mathevet P., Bongiovanni M.
ISSN
1097-0339 (Electronic)
ISSN-L
1097-0339
Publication state
Published
Issued date
06/2019
Peer-reviewed
Oui
Volume
47
Number
6
Pages
603-607
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Uterine tumors resembling ovarian sex-cord tumors (UTROSCTs) are rare uterine neoplasms of uncertain etiology that resemble the sex cord tumors of the ovary and display a combined sex cord, epithelial, and smooth muscle immunophenotype. Most tumors are associated with a benign clinical course. We report the first cytological description of uterine UTROSCTs in liquid-based cervical cytology (LBC). A menopausal woman was discovered to have a uterine intraluminal polypoid mass protruding through the vagina. A Pap test was performed, and the LBC preparation showed isolated tumor cells with scant cytoplasm and slightly irregular, ovoid nuclei with fine chromatin and small nucleoli. Final histological evaluation identified a UTROSCT. This diagnostic possibility, albeit rare, should be included in the differential diagnosis when isolated malignant-appearing adenocarcinomatous cells are seen in women in the above scenario. As these features are not specific, they may result in misinterpretation with tumors that are more common and aggressive.
Keywords
Pap smears, differential diagnosis, liquid-based cytology, uterine tumor resembling ovarian sex-cord tumor
Pubmed
Web of science
Create date
25/02/2019 13:19
Last modification date
20/08/2019 16:11
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