Treatment of gastroduodenal Crohn's disease.

Details

Serval ID
serval:BIB_A4E56270FA3C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Treatment of gastroduodenal Crohn's disease.
Journal
Digestion
Author(s)
Mottet C., Juillerat P., Gonvers J.J., Michetti P., Burnand B., Vader J.P., Felley C., Froehlich F.
ISSN
0012-2823
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
71
Number
1
Pages
37-40
Language
english
Notes
Publication types: Journal Article ; Review - Publication Status: ppublish
Abstract
Symptomatic gastroduodenal manifestations of Crohn's disease (CD) are rare, with less than 4% of patients being clinically symptomatic. Gastroduodenal involvement may, however, be found endoscopically in 20% and in up to 40% of cases histologically, most frequently as Helicobacter pylori-negative focal gastritis, usually in patients with concomitant distal ileal disease. In practice, the activity of concomitant distal CD usually determines the indication for therapy, except in the presence of obstructive gastroduodenal symptoms. With the few data available, it seems correct to say that localized gastroduodenal disease should be treated with standard medical therapy used for more distal disease, with the exception of sulfasalazine and mesalanine with pH-dependent release. Presence of symptoms of obstruction needs aggressive therapy. If medical therapy with steroids and immunomodulatory drugs does not alleviate the symptoms, balloon dilation and surgery are the options to consider.
Keywords
Balloon Dilatation, Crohn Disease, Glucocorticoids, Humans, Immunologic Factors, Intestinal Obstruction, Treatment Outcome
Pubmed
Web of science
Create date
25/01/2008 15:58
Last modification date
20/08/2019 15:10
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