Treatment of gastroduodenal Crohn's disease.

Détails

ID Serval
serval:BIB_A4E56270FA3C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Treatment of gastroduodenal Crohn's disease.
Périodique
Digestion
Auteur(s)
Mottet C., Juillerat P., Gonvers J.J., Michetti P., Burnand B., Vader J.P., Felley C., Froehlich F.
ISSN
0012-2823
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
71
Numéro
1
Pages
37-40
Langue
anglais
Notes
Publication types: Journal Article ; Review - Publication Status: ppublish
Résumé
Symptomatic gastroduodenal manifestations of Crohn's disease (CD) are rare, with less than 4% of patients being clinically symptomatic. Gastroduodenal involvement may, however, be found endoscopically in 20% and in up to 40% of cases histologically, most frequently as Helicobacter pylori-negative focal gastritis, usually in patients with concomitant distal ileal disease. In practice, the activity of concomitant distal CD usually determines the indication for therapy, except in the presence of obstructive gastroduodenal symptoms. With the few data available, it seems correct to say that localized gastroduodenal disease should be treated with standard medical therapy used for more distal disease, with the exception of sulfasalazine and mesalanine with pH-dependent release. Presence of symptoms of obstruction needs aggressive therapy. If medical therapy with steroids and immunomodulatory drugs does not alleviate the symptoms, balloon dilation and surgery are the options to consider.
Mots-clé
Balloon Dilatation, Crohn Disease, Glucocorticoids, Humans, Immunologic Factors, Intestinal Obstruction, Treatment Outcome
Pubmed
Web of science
Création de la notice
25/01/2008 15:58
Dernière modification de la notice
20/08/2019 15:10
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