Unusually strong lipophilicity of 'fat' or 'super' amino-acids, including a new reference value for glycine.

Details

Serval ID
serval:BIB_9B0769B270FC
Type
Article: article from journal or magazin.
Collection
Publications
Title
Unusually strong lipophilicity of 'fat' or 'super' amino-acids, including a new reference value for glycine.
Journal
Experientia
Author(s)
Fauchère J.L., Do K.Q., Jow P.Y., Hansch C.
ISSN
0014-4754 (Print)
ISSN-L
0014-4754
Publication state
Published
Issued date
1980
Peer-reviewed
Oui
Volume
36
Number
10
Pages
1203-1204
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
Lipophilic, steric, electronic, and enzyme resistance characteristics of carboranylalanine, adamantylalanine, neopentylglycine and tert-butylglycine are described. The first 2 amino-acids display lipophilicities 2 orders of magnitude higher than tryptophan.
Keywords
Amino Acids, Enzymes/metabolism, Glycine, Molecular Conformation, Protein Binding, Structure-Activity Relationship, Water
Pubmed
Web of science
Create date
06/03/2014 15:49
Last modification date
20/08/2019 15:02
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