The cervical spine in calcium pyrophosphate dihydrate deposition disease. A prevalent case-control study.

Details

Serval ID
serval:BIB_96C3070A8F95
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The cervical spine in calcium pyrophosphate dihydrate deposition disease. A prevalent case-control study.
Journal
Journal of Rheumatology
Author(s)
Finckh A., Van Linthoudt D., Duvoisin B., Bovay P., Gerster J.C.
ISSN
0315-162X
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
31
Number
3
Pages
545-549
Language
english
Notes
Publication types: Journal Article
Abstract
OBJECTIVE: To test the hypothesis that calcium pyrophosphate dihydrate (CPPD) deposition disease is a risk factor for neck pain. METHODS: A prevalent case-control study was conducted to assess cervical calcifications and neck pain between patients with and without known peripheral CPPD deposition disease. CPPD cases were included if diagnosed with CPPD deposition disease of peripheral joints, and excluded if their chief complaint was neck pain. Controls were randomly selected among consecutive patients, hospitalized for conditions unrelated to CPPD deposition disease or neck pain, and matched to CPPD cases by age and sex. Cervical calcifications were assessed by lateral cervical radiographs and computed tomography scans of the upper cervical spine; neck pain and cervical function were appraised by a validated questionnaire. RESULTS: Cervical calcifications were found in 24 out of 35 patients (69%) in the CPPD group compared to 4 out of 35 patients (11%) in the control group (p < 0.001). Patients with CPPD deposition disease reported significantly more neck pain and discomfort than controls (p < 0.001), and were 5 times more likely to report any neck pain (odds ratio 5.5; 95% confidence interval: 1.9, 21.9). Among male patients, more extensive cervical calcified deposits correlated with more severe neck pain (rs = 0.58, p = 0.03). CONCLUSION: These results suggest that CPPD deposition disease frequently involves the cervical spine and may be associated with the development of neck pain.
Keywords
Aged, Aged, 80 and over, Case-Control Studies, Cervical Vertebrae, Chondrocalcinosis, Cross-Sectional Studies, Female, Humans, Male, Neck Pain, Risk Factors, Single-Blind Method, Switzerland, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
11/04/2008 12:20
Last modification date
20/08/2019 14:58
Usage data