Patterns of positive selection in seven ant genomes.

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State: Serval
Version: Final published version
Serval ID
serval:BIB_95722591AAD3
Type
Article: article from journal or magazin.
Collection
Publications
Title
Patterns of positive selection in seven ant genomes.
Journal
Molecular Biology and Evolution
Author(s)
Roux J., Privman E., Moretti S., Daub J.T., Robinson-Rechavi M., Keller L.
ISSN
1537-1719 (Electronic)
ISSN-L
0737-4038
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
31
Number
7
Pages
1661-1685
Language
english
Abstract
The evolution of ants is marked by remarkable adaptations that allowed the development of very complex social systems. To identify how ant-specific adaptations are associated with patterns of molecular evolution, we searched for signs of positive selection on amino-acid changes in proteins. We identified 24 functional categories of genes which were enriched for positively selected genes in the ant lineage. We also reanalyzed genome-wide data sets in bees and flies with the same methodology to check whether positive selection was specific to ants or also present in other insects. Notably, genes implicated in immunity were enriched for positively selected genes in the three lineages, ruling out the hypothesis that the evolution of hygienic behaviors in social insects caused a major relaxation of selective pressure on immune genes. Our scan also indicated that genes implicated in neurogenesis and olfaction started to undergo increased positive selection before the evolution of sociality in Hymenoptera. Finally, the comparison between these three lineages allowed us to pinpoint molecular evolution patterns that were specific to the ant lineage. In particular, there was ant-specific recurrent positive selection on genes with mitochondrial functions, suggesting that mitochondrial activity was improved during the evolution of this lineage. This might have been an important step toward the evolution of extreme lifespan that is a hallmark of ants.
Keywords
Drosophila, Hymenoptera, aging, bees, comparative genomics, dN/dS, immunity, lifespan, metabolism, neurogenesis, olfactory receptors, sociality
Pubmed
Web of science
Open Access
Yes
Create date
15/04/2014 17:18
Last modification date
08/05/2019 22:17
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