Microbial interactions in theory and practice: when are measurements compatible with models?

Details

Serval ID
serval:BIB_89918B5E96B2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Microbial interactions in theory and practice: when are measurements compatible with models?
Journal
Current opinion in microbiology
Author(s)
Picot A., Shibasaki S., Meacock O.J., Mitri S.
ISSN
1879-0364 (Electronic)
ISSN-L
1369-5274
Publication state
Published
Issued date
06/07/2023
Peer-reviewed
Oui
Volume
75
Pages
102354
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Most predictive models of ecosystem dynamics are based on interactions between organisms: their influence on each other's growth and death. We review here how theoretical approaches are used to extract interaction measurements from experimental data in microbiology, particularly focusing on the generalised Lotka-Volterra (gLV) framework. Though widely used, we argue that the gLV model should be avoided for estimating interactions in batch culture - the most common, simplest and cheapest in vitro approach to culturing microbes. Fortunately, alternative approaches offer a way out of this conundrum. Firstly, on the experimental side, alternatives such as the serial-transfer and chemostat systems more closely match the theoretical assumptions of the gLV model. Secondly, on the theoretical side, explicit organism-environment interaction models can be used to study the dynamics of batch-culture systems. We hope that our recommendations will increase the tractability of microbial model systems for experimentalists and theoreticians alike.
Pubmed
Open Access
Yes
Create date
13/07/2023 14:06
Last modification date
01/08/2023 6:55
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