Verb and noun generation tasks in Huntington's disease.

Details

Serval ID
serval:BIB_87A5AB4CB7F3
Type
Article: article from journal or magazin.
Collection
Publications
Title
Verb and noun generation tasks in Huntington's disease.
Journal
Movement Disorders
Author(s)
Péran P., Démonet J.F., Pernet C., Cardebat D.
ISSN
0885-3185 (Print)
ISSN-L
0885-3185
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
19
Number
5
Pages
565-571
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish. PDF type: Brief Report
Abstract
We compared noun- and verb-generation tasks in a demented group (n = 9, Dementia Rating Scale < or = 129) and in a non-demented group (n = 17, Dementia Rating Scale > 129) of Huntington's disease (HD) patients compared to 26 matched normal subjects. We did not find a specific deficit for verb production in non-demented patients who had a performance similar to but weaker than that of the controls across the four tasks. The profile of results was different in the demented group because, apart from a global deficit whatever the task in comparison with both non-demented and control groups, the demented patients exhibited increased difficulties in the two tasks implying verb production. The deficit of verb production observed in demented HD patients is discussed in relation to the damage to the motor loop in HD patients at later stages of disease.
Keywords
Aphasia, Broca/diagnosis, Aphasia, Broca/etiology, Cognition Disorders/diagnosis, Cognition Disorders/etiology, Female, Frontal Lobe/physiopathology, Humans, Huntington Disease/complications, Huntington Disease/genetics, Male, Middle Aged, Nerve Tissue Proteins, Neuropsychological Tests, Nuclear Proteins, Proteins/genetics, Severity of Illness Index, Temporal Lobe/physiopathology, Vocabulary
Pubmed
Web of science
Create date
24/03/2013 18:40
Last modification date
20/08/2019 14:46
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