Impact of Latent Tuberculosis on Diabetes.
Details
Serval ID
serval:BIB_878BF720EE16
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of Latent Tuberculosis on Diabetes.
Journal
The Journal of infectious diseases
Working group(s)
Swiss HIV Cohort Study
Contributor(s)
Abela I., Aebi-Popp K., Anagnostopoulos A., Battegay M., Bernasconi E., Braun D.L., Bucher H.C., Calmy A., Cavassini M., Ciuffi A., Dollenmaier G., Egger M., Elzi L., Fehr J., Fellay J., Furrer H., Fux C.A., Günthard H.F., Hachfeld A., Haerry D., Hasse B., Hirsch H.H., Hoffmann M., Hösli I., Huber M., Kahlert C.R., Kaiser L., Keiser O., Klimkait T., Kouyos R.D., Kovari H., Kusejko K., Martinetti G., Martinez de Tejada B., Marzolini C., Metzner K.J., Müller N., Nemeth J., Nicca D., Paioni P., Pantaleo G., Perreau M., Rauch A., Schmid P., Speck R., Stöckle M., Tarr P., Trkola A., Wandeler G., Yerly S.
ISSN
1537-6613 (Electronic)
ISSN-L
0022-1899
Publication state
Published
Issued date
15/06/2022
Peer-reviewed
Oui
Volume
225
Number
12
Pages
2229-2234
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well characterized whether LTBI is associated with an increased risk of developing DM. We investigated the link between LTBI and DM in people living with HIV in the Swiss HIV Cohort Study via time-dependent Cox proportional hazards models. We found that LTBI significantly increased the risk of developing DM (HR = 1.47), which was robust across different adjustment and censoring techniques. Our results thus suggest that LTBI may be associated with an increased risk of developing DM.
Keywords
Cohort Studies, Diabetes Mellitus, Type 2/complications, HIV Infections/complications, Humans, Latent Tuberculosis/complications, Latent Tuberculosis/epidemiology, heterologous immunity, inflammatory diseases, innate immunity, latent tuberculosis, low-grade inflammation, type-2 diabetes mellitus
Pubmed
Web of science
Open Access
Yes
Create date
19/02/2022 11:12
Last modification date
22/07/2022 6:38