Evolutionary dynamics of coding and non-coding transcriptomes.

Details

Serval ID
serval:BIB_861B8E3D5B9C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Evolutionary dynamics of coding and non-coding transcriptomes.
Journal
Nature Reviews. Genetics
Author(s)
Necsulea A., Kaessmann H.
ISSN
1471-0064 (Electronic)
ISSN-L
1471-0056
Publication state
Published
Issued date
2014
Volume
15
Number
11
Pages
734-748
Language
english
Abstract
Gene expression changes may underlie much of phenotypic evolution. The development of high-throughput RNA sequencing protocols has opened the door to unprecedented large-scale and cross-species transcriptome comparisons by allowing accurate and sensitive assessments of transcript sequences and expression levels. Here, we review the initial wave of the new generation of comparative transcriptomic studies in mammals and vertebrate outgroup species in the context of earlier work. Together with various large-scale genomic and epigenomic data, these studies have unveiled commonalities and differences in the dynamics of gene expression evolution for various types of coding and non-coding genes across mammalian lineages, organs, developmental stages, chromosomes and sexes. They have also provided intriguing new clues to the regulatory basis and phenotypic implications of evolutionary gene expression changes.
Pubmed
Web of science
Create date
04/12/2014 11:17
Last modification date
20/08/2019 14:45
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