Evolutionary dynamics of coding and non-coding transcriptomes.

Détails

ID Serval
serval:BIB_861B8E3D5B9C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Evolutionary dynamics of coding and non-coding transcriptomes.
Périodique
Nature Reviews. Genetics
Auteur⸱e⸱s
Necsulea A., Kaessmann H.
ISSN
1471-0064 (Electronic)
ISSN-L
1471-0056
Statut éditorial
Publié
Date de publication
2014
Volume
15
Numéro
11
Pages
734-748
Langue
anglais
Résumé
Gene expression changes may underlie much of phenotypic evolution. The development of high-throughput RNA sequencing protocols has opened the door to unprecedented large-scale and cross-species transcriptome comparisons by allowing accurate and sensitive assessments of transcript sequences and expression levels. Here, we review the initial wave of the new generation of comparative transcriptomic studies in mammals and vertebrate outgroup species in the context of earlier work. Together with various large-scale genomic and epigenomic data, these studies have unveiled commonalities and differences in the dynamics of gene expression evolution for various types of coding and non-coding genes across mammalian lineages, organs, developmental stages, chromosomes and sexes. They have also provided intriguing new clues to the regulatory basis and phenotypic implications of evolutionary gene expression changes.
Pubmed
Web of science
Création de la notice
04/12/2014 12:17
Dernière modification de la notice
20/08/2019 15:45
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