Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.

Details

Serval ID
serval:BIB_84ABF5986D70
Type
Article: article from journal or magazin.
Collection
Publications
Title
Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.
Journal
Science
Author(s)
Neafsey D.E., Waterhouse R.M., Abai M.R., Aganezov S.S., Alekseyev M.A., Allen J.E., Amon J., Arcà B., Arensburger P., Artemov G., Assour L.A., Basseri H., Berlin A., Birren B.W., Blandin S.A., Brockman A.I., Burkot T.R., Burt A., Chan C.S., Chauve C., Chiu J.C., Christensen M., Costantini C., Davidson V.L., Deligianni E., Dottorini T., Dritsou V., Gabriel S.B., Guelbeogo W.M., Hall A.B., Han M.V., Hlaing T., Hughes D.S., Jenkins A.M., Jiang X., Jungreis I., Kakani E.G., Kamali M., Kemppainen P., Kennedy R.C., Kirmitzoglou I.K., Koekemoer L.L., Laban N., Langridge N., Lawniczak M.K., Lirakis M., Lobo N.F., Lowy E., MacCallum R.M., Mao C., Maslen G., Mbogo C., McCarthy J., Michel K., Mitchell S.N., Moore W., Murphy K.A., Naumenko A.N., Nolan T., Novoa E.M., O'Loughlin S., Oringanje C., Oshaghi M.A., Pakpour N., Papathanos P.A., Peery A.N., Povelones M., Prakash A., Price D.P., Rajaraman A., Reimer L.J., Rinker D.C., Rokas A., Russell T.L., Sagnon N., Sharakhova M.V., Shea T., Simão F.A., Simard F., Slotman M.A., Somboon P., Stegniy V., Struchiner C.J., Thomas G.W., Tojo M., Topalis P., Tubio J.M., Unger M.F., Vontas J., Walton C., Wilding C.S., Willis J.H., Wu Y.C., Yan G., Zdobnov E.M., Zhou X., Catteruccia F., Christophides G.K., Collins F.H., Cornman R.S., Crisanti A., Donnelly M.J., Emrich S.J., Fontaine M.C., Gelbart W., Hahn M.W., Hansen I.A., Howell P.I., Kafatos F.C., Kellis M., Lawson D., Louis C., Luckhart S., Muskavitch M.A., Ribeiro J.M., Riehle M.A., Sharakhov I.V., Tu Z., Zwiebel L.J., Besansky N.J.
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
347
Number
6217
Pages
1258522
Language
english
Abstract
Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. To investigate the genomic basis of vectorial capacity and explore new avenues for vector control, we sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution. Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila. Some determinants of vectorial capacity, such as chemosensory genes, do not show elevated turnover but instead diversify through protein-sequence changes. This dynamism of anopheline genes and genomes may contribute to their flexible capacity to take advantage of new ecological niches, including adapting to humans as primary hosts.

Keywords
Animals, Anopheles/classification, Anopheles/genetics, Base Sequence, Chromosomes, Insect/genetics, Drosophila/genetics, Evolution, Molecular, Genome, Insect, Humans, Insect Vectors/classification, Insect Vectors/genetics, Malaria/transmission, Molecular Sequence Data, Phylogeny, Sequence Alignment
Pubmed
Web of science
Open Access
Yes
Create date
20/09/2017 10:52
Last modification date
08/05/2019 21:20
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