Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity

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Version: Final published version
Serval ID
serval:BIB_84A51323B2E3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity
Journal
Nature Communications
Author(s)
Pietra S., Gustavsson A., Kiefer C., Kalmbach L., Hörstedt P., Ikeda Y., Stepanova A.N., Alonso J.M., Grebe M.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
4
Pages
2779
Language
english
Notes
Publication types: Article ; research-article Identifiant PubMed Central: PMC3868209
Abstract
The orientation of cell division and the coordination of cell polarity within the plane of the tissue layer (planar polarity) contribute to shape diverse multicellular organisms. The root of Arabidopsis thaliana displays regularly oriented cell divisions, cell elongation and planar polarity providing a plant model system to study these processes. Here we report that the SABRE protein, which shares similarity with proteins of unknown function throughout eukaryotes, has important roles in orienting cell division and planar polarity. SABRE localizes at the plasma membrane, endomembranes, mitotic spindle and cell plate. SABRE stabilizes the orientation of CLASP-labelled preprophase band microtubules predicting the cell division plane, and of cortical microtubules driving cell elongation. During planar polarity establishment, sabre is epistatic to clasp at directing polar membrane domains of Rho-of-plant GTPases. Our findings mechanistically link SABRE to CLASP-dependent microtubule organization, shedding new light on the function of SABRE-related proteins in eukaryotes.
Keywords
Arabidopsis/cytology, Arabidopsis/physiology, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, Cell Division/physiology, Cell Polarity/physiology, Gene Expression Regulation, Plant/physiology, Intracellular Signaling Peptides and Proteins/genetics, Intracellular Signaling Peptides and Proteins/metabolism, Microtubule-Associated Proteins/genetics, Microtubule-Associated Proteins/metabolism
Pubmed
Web of science
Open Access
Yes
Create date
11/07/2016 10:04
Last modification date
20/08/2019 14:44
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