Maintenance of neuronal expression of calbindin by a muscular extract in cultures of chick dorsal root ganglion cells.

Details

Serval ID
serval:BIB_838274272F7F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Maintenance of neuronal expression of calbindin by a muscular extract in cultures of chick dorsal root ganglion cells.
Journal
Neuroscience letters
Author(s)
Barakat I., Droz B.
ISSN
0304-3940
Publication state
Published
Issued date
1989
Peer-reviewed
Oui
Volume
99
Number
1-2
Pages
1-5
Language
english
Abstract
Calbindin D-28K is a calcium-binding protein which is expressed by subpopulations of dorsal root ganglion cells cultured from 10-day-old (E10) chick embryos. After 7 or 10 days of culture, more than 20% of the ganglion cells are immunostained by an anticalbindin-antiserum; however, after 14 days of culture, the proportion drops to 10%. This fall can be prevented by addition of muscle extract to cultures at 10 days. Thus the transitory expression of calbindin-immunoreactivity by responsive sensory neurons would be not only induced but also maintained by a differentiation factor of muscular origin.
Keywords
Animals, Calcium-Binding Protein, Vitamin D-Dependent, Cells, Cultured, Chick Embryo, Ganglia, Spinal, Gene Expression Regulation, Muscles, Time Factors, Tissue Extracts
Pubmed
Web of science
Create date
30/03/2009 10:40
Last modification date
20/08/2019 15:43
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