Value of cardiophrenic angle lymph node for the diagnosis of colorectal peritoneal carcinomatosis.
Details
Serval ID
serval:BIB_7AF32D1BB5D1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Value of cardiophrenic angle lymph node for the diagnosis of colorectal peritoneal carcinomatosis.
Journal
European journal of cancer
ISSN
1879-0852 (Electronic)
ISSN-L
0959-8049
Publication state
Published
Issued date
12/2013
Peer-reviewed
Oui
Volume
49
Number
18
Pages
3798-3805
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Cardiophrenic angle lymph nodes (CPALN) have been reported in patients with abdominopelvic malignancies. We aimed to assess whether the presence of CPALN is associated with peritoneal carcinomatosis (PC) in colorectal cancer.
Between 2007 and 2011, 550 patients with colorectal cancer, including 165 (30%) with PC, had undergone surgery with complete peritoneal exploration. We retrospectively reviewed preoperative CT scans for the presence of CPALN and assessed its association with confirmed PC by univariate and multivariate analyses.
CPALN were present in 123 (75%) patients with PC, but absent in 263 (68%) patients without PC (Se: 0.72; Sp: 0.68; PPV: 0.49; NPV: 0.85; [OR], 3.3; p<0.001). PC was the only factor independently associated with CPALN in the multivariate analysis. CPALN was not correlated with the presence of liver metastases. 99 of the 165 patients with PC (62%) had visible signs of PC on CT scan. Among the remaining 66 patients, CPALN were the only potential sign of PC in 41 (62%), (Se 0.62, Sp 0.68, PPV 0.24, and NPV 0.92).
The detection of CPALN on CT may be of valuable help for the diagnosis of PC in patients with CRC.
Between 2007 and 2011, 550 patients with colorectal cancer, including 165 (30%) with PC, had undergone surgery with complete peritoneal exploration. We retrospectively reviewed preoperative CT scans for the presence of CPALN and assessed its association with confirmed PC by univariate and multivariate analyses.
CPALN were present in 123 (75%) patients with PC, but absent in 263 (68%) patients without PC (Se: 0.72; Sp: 0.68; PPV: 0.49; NPV: 0.85; [OR], 3.3; p<0.001). PC was the only factor independently associated with CPALN in the multivariate analysis. CPALN was not correlated with the presence of liver metastases. 99 of the 165 patients with PC (62%) had visible signs of PC on CT scan. Among the remaining 66 patients, CPALN were the only potential sign of PC in 41 (62%), (Se 0.62, Sp 0.68, PPV 0.24, and NPV 0.92).
The detection of CPALN on CT may be of valuable help for the diagnosis of PC in patients with CRC.
Keywords
Adult, Aged, Aged, 80 and over, Colorectal Neoplasms/pathology, Diaphragm, Female, Humans, Logistic Models, Lymph Nodes/pathology, Lymphatic Metastasis, Male, Middle Aged, Multivariate Analysis, Pericardium, Peritoneal Neoplasms/diagnosis, Peritoneal Neoplasms/secondary, Peritoneum/diagnostic imaging, Prognosis, Retrospective Studies, Sensitivity and Specificity, Tomography, X-Ray Computed, Young Adult, Colorectal cancer, Early diagnosis, Lymph nodes, Peritoneal cavity
Pubmed
Web of science
Create date
16/09/2016 11:13
Last modification date
20/05/2025 15:34
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