Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation.

Details

Serval ID
serval:BIB_768523736025
Type
Article: article from journal or magazin.
Collection
Publications
Title
Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation.
Journal
Transplant International : Official Journal of the European Society For Organ Transplantation
Author(s)
Lerut J.P., Orlando G., Sempoux C., Ciccarelli O., Van Beers B.E., Danse E., Horsmans Y., Rahier J., Roggen F.
ISSN
0934-0874 (Print)
ISSN-L
0934-0874
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
17
Number
4
Pages
202-207
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Hepatic epithelioid haemangioendotheliomas (HEHEs) are rare, low-grade vascular tumours. Five adults with HEHEs and one adult with a vascular tumour showing combined features of haemangioma and haemangioendothelioma underwent liver transplantation. Two HEHE patients had extrahepatic metastases at the time of transplantation. Median survival time following diagnosis was 10.7 years (range 40 months to 195 months). One patient needed resection of a HEHE in the breast 13 years post-transplantation. All six patients are surviving free from disease 22 to 166 months after transplantation (median 77 months). One HEHE-patient who had been treated for 8 years for vertebral and cerebral localisations is free of disease without immunosuppression 56 months after transplantation. We can conclude that liver transplantation is a valuable treatment for hepatic haemangioendothelioma, even in cases of extrahepatic localisation of the disease.
Keywords
Adult, Disease-Free Survival, Female, Hemangioendothelioma, Epithelioid/surgery, Humans, Liver/pathology, Liver Neoplasms/surgery, Liver Transplantation, Male, Middle Aged, Time Factors, Treatment Outcome
Pubmed
Web of science
Create date
20/10/2016 16:24
Last modification date
20/08/2019 14:33
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