Article: article from journal or magazin.
Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation.
Transplant International : Official Journal of the European Society For Organ Transplantation
Publication types: Journal ArticlePublication Status: ppublish
Hepatic epithelioid haemangioendotheliomas (HEHEs) are rare, low-grade vascular tumours. Five adults with HEHEs and one adult with a vascular tumour showing combined features of haemangioma and haemangioendothelioma underwent liver transplantation. Two HEHE patients had extrahepatic metastases at the time of transplantation. Median survival time following diagnosis was 10.7 years (range 40 months to 195 months). One patient needed resection of a HEHE in the breast 13 years post-transplantation. All six patients are surviving free from disease 22 to 166 months after transplantation (median 77 months). One HEHE-patient who had been treated for 8 years for vertebral and cerebral localisations is free of disease without immunosuppression 56 months after transplantation. We can conclude that liver transplantation is a valuable treatment for hepatic haemangioendothelioma, even in cases of extrahepatic localisation of the disease.
Adult, Disease-Free Survival, Female, Hemangioendothelioma, Epithelioid/surgery, Humans, Liver/pathology, Liver Neoplasms/surgery, Liver Transplantation, Male, Middle Aged, Time Factors, Treatment Outcome
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