Mise à jour sur l'hépatite E [An update on hepatitis E].

Details

Serval ID
serval:BIB_7488FCBC71F0
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Mise à jour sur l'hépatite E [An update on hepatitis E].
Journal
Revue Médicale Suisse
Author(s)
Hiroz P., Gouttenoire J., Dao Thi V.L., Sahli R., Telenti A., Moradpour D., Doerig C.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
396
Pages
1594-1598
Language
french
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Abstract
The hepatitis E virus (HEV) is an RNA virus transmitted via the fecal-oral route or through uncooked animal meat products. Of the 4 known genotypes, genotype 3 is responsible for autochthonous infections in industrialized countries, with a seroprevalence in Switzerland estimated as high as 22%. The majority of infections is asymptomatic but a minority of patients, notably men over 50 or with underlying liver disease, can present with severe acute hepatitis. Chronic hepatitis E with HEV of genotype 3 has been observed in immunosuppressed patients, mostly transplant recipients. Serology is not sufficiently sensitive, especially in immunosuppressed patients, making PCR identification the preferred test for diagnosing active infection. Ribavirin or interferon-alpha can be used to treat chronic hepatitis E if reduction of immunosuppressive treatment does not result in viral elimination.
Keywords
Adolescent, Adult, Age Factors, Antiviral Agents/therapeutic use, Female, Genotype, Hepatitis E/epidemiology, Hepatitis E/therapy, Hepatitis E virus/genetics, Hepatitis E virus/isolation & purification, Humans, Immunocompromised Host, Male, Middle Aged, Risk Factors, Seroepidemiologic Studies, Sex Factors, Switzerland/epidemiology, Young Adult
Pubmed
Create date
16/02/2014 12:54
Last modification date
20/08/2019 15:32
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