Role of Chlamydia trachomatis and emerging Chlamydia-related bacteria in ectopic pregnancy in Vietnam

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State: Public
Version: After imprimatur
Serval ID
serval:BIB_73CD43DF82E3
Type
A Master's thesis.
Publication sub-type
Master (thesis) (master)
Collection
Publications
Institution
Title
Role of Chlamydia trachomatis and emerging Chlamydia-related bacteria in ectopic pregnancy in Vietnam
Author(s)
HORNUNG S.
Director(s)
BAUD D.
Institution details
Université de Lausanne, Faculté de biologie et médecine
Publication state
Accepted
Issued date
2014
Language
english
Number of pages
22
Abstract
In this case-control study, we investigated the seroprevalence and molecular evidence of Chlamydia trachomatis and Waddlia chondrophila in ectopic pregnancies (EP) and uneventful control (C) pregnancies in 343 women from Vietnam. Whereas presence of Chlamydia trachomatis IgG was strongly associated with EP (adjusted Odds Ratio [aOR] 5.41; 95% Confidence Intervals [95%CI] 2.58-11.32), its DNA remained undetected in all tubal lesions. We confirmed an independent association between antibodies against Waddlia and previous miscarriage (aOR 1.87, 95%CI 1.02-3.42). Further investigations are needed to understand the clinical significance of Waddlia high seroprevalence (25.9% in C) in this urban population.
Keywords
Chlamydia-related bacteria, adverse pregnancy outcome, genital tract infection, intracellular bacteria, ectopic pregnancy
Create date
07/09/2015 8:57
Last modification date
20/08/2019 14:31
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