A Master's thesis.
Master (thesis) (master)
Role of Chlamydia trachomatis and emerging Chlamydia-related bacteria in ectopic pregnancy in Vietnam
Université de Lausanne, Faculté de biologie et médecine
Number of pages
In this case-control study, we investigated the seroprevalence and molecular evidence of Chlamydia trachomatis and Waddlia chondrophila in ectopic pregnancies (EP) and uneventful control (C) pregnancies in 343 women from Vietnam. Whereas presence of Chlamydia trachomatis IgG was strongly associated with EP (adjusted Odds Ratio [aOR] 5.41; 95% Confidence Intervals [95%CI] 2.58-11.32), its DNA remained undetected in all tubal lesions. We confirmed an independent association between antibodies against Waddlia and previous miscarriage (aOR 1.87, 95%CI 1.02-3.42). Further investigations are needed to understand the clinical significance of Waddlia high seroprevalence (25.9% in C) in this urban population.
Chlamydia-related bacteria, adverse pregnancy outcome, genital tract infection, intracellular bacteria, ectopic pregnancy
Last modification date