Genus-wide characterization of bumblebee genomes provides insights into their evolution and variation in ecological and behavioral traits.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_7245D0A9D57D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Genus-wide characterization of bumblebee genomes provides insights into their evolution and variation in ecological and behavioral traits.
Journal
Molecular biology and evolution
Author(s)
Sun C., Huang J., Wang Y., Zhao X., Su L., Thomas GWC, Zhao M., Zhang X., Jungreis I., Kellis M., Vicario S., Sharakhov I.V., Bondarenko S.M., Hasselmann M., Kim C.N., Paten B., Penso-Dolfin L., Wang L., Chang Y., Gao Q., Ma L., Ma L., Zhang Y., Zhang H., Zhang H., Ruzzante L., Robertson H.M., Zhu Y., Liu Y., Yang H., Ding L., Wang Q., Ma D., Xu W., Liang C., Itgen M.W., Mee L., Cao G., Zhang Z., Sadd B.M., Hahn M., Schaack S., Barribeau S.M., Williams P.H., Waterhouse R.M., Mueller R.L.
ISSN
1537-1719 (Electronic)
ISSN-L
0737-4038
Publication state
Published
Issued date
18/09/2020
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Bumblebees are a diverse group of globally important pollinators in natural ecosystems and for agricultural food production. With both eusocial and solitary life-cycle phases, and some social parasite species, they are especially interesting models to understand social evolution, behavior, and ecology. Reports of many species in decline point to pathogen transmission, habitat loss, pesticide usage, and global climate change, as interconnected causes. These threats to bumblebee diversity make our reliance on a handful of well-studied species for agricultural pollination particularly precarious. To broadly sample bumblebee genomic and phenotypic diversity, we de novo sequenced and assembled the genomes of 17 species, representing all 15 subgenera, producing the first genus-wide quantification of genetic and genomic variation potentially underlying key ecological and behavioral traits. The species phylogeny resolves subgenera relationships while incomplete lineage sorting likely drives high levels of gene tree discordance. Five chromosome-level assemblies show a stable 18-chromosome karyotype, with major rearrangements creating 25 chromosomes in social parasites. Differential transposable element activity drives changes in genome sizes, with putative domestications of repetitive sequences influencing gene coding and regulatory potential. Dynamically evolving gene families and signatures of positive selection point to genus-wide variation in processes linked to foraging, diet and metabolism, immunity and detoxification, as well as adaptations for life at high altitudes. Our study reveals how bumblebee genes and genomes have evolved across the Bombus phylogeny and identifies variations potentially linked to key ecological and behavioral traits of these important pollinators.
Keywords
Bombus, gene family evolution, genome assembly, genome evolution, insect diversity
Pubmed
Open Access
Yes
Funding(s)
Swiss National Science Foundation / Careers / PP00P3_170664
Create date
28/09/2020 11:49
Last modification date
08/11/2020 7:09
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