The Vaccine Formulation Laboratory: a platform for access to adjuvants.

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State: Public
Version: author
Serval ID
serval:BIB_710E7C5456F0
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The Vaccine Formulation Laboratory: a platform for access to adjuvants.
Journal
Vaccine
Author(s)
Collin N., Dubois P.M.
ISSN
1873-2518 (Electronic)
ISSN-L
0264-410X
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
29 Suppl 1
Number
Suppl 1
Pages
A37-A39
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Review Publication Status: ppublish
Abstract
Adjuvants are increasingly used by the vaccine research and development community, particularly for their ability to enhance immune responses and for their dose-sparing properties. However, they are not readily available to the majority of public sector vaccine research groups, and even those with access to suitable adjuvants may still fail in the development of their vaccines because of lack of knowledge on how to correctly formulate the adjuvants. This shortcoming led the World Health Organization to advocate for the establishment of the Vaccine Formulation Laboratory at the University of Lausanne, Switzerland. The primary mission of the laboratory is to transfer adjuvants and formulation technology free of intellectual property rights to academic institutions, small biotechnology companies and developing countries vaccine manufacturers. In this context, the transfer of an oil-in-water emulsion to Bio Farma, an Indonesian vaccine manufacturer, was initiated to increase domestic pandemic influenza vaccine production capacity as part of the national pandemic influenza preparedness plan.
Keywords
Adjuvants, Immunologic/administration & dosage, Chemistry, Pharmaceutical/methods, Humans, Switzerland, Technology Transfer, Technology, Pharmaceutical/economics, Technology, Pharmaceutical/legislation & jurisprudence, Vaccines/chemistry, Vaccines/immunology, World Health Organization
Pubmed
Web of science
Open Access
Yes
Create date
27/10/2011 13:07
Last modification date
20/08/2019 14:29
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