The Vaccine Formulation Laboratory: a platform for access to adjuvants.

Détails

Ressource 1Télécharger: BIB_710E7C5456F0.P001.pdf (181.48 [Ko])
Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_710E7C5456F0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
The Vaccine Formulation Laboratory: a platform for access to adjuvants.
Périodique
Vaccine
Auteur⸱e⸱s
Collin N., Dubois P.M.
ISSN
1873-2518 (Electronic)
ISSN-L
0264-410X
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
29 Suppl 1
Numéro
Suppl 1
Pages
A37-A39
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Review Publication Status: ppublish
Résumé
Adjuvants are increasingly used by the vaccine research and development community, particularly for their ability to enhance immune responses and for their dose-sparing properties. However, they are not readily available to the majority of public sector vaccine research groups, and even those with access to suitable adjuvants may still fail in the development of their vaccines because of lack of knowledge on how to correctly formulate the adjuvants. This shortcoming led the World Health Organization to advocate for the establishment of the Vaccine Formulation Laboratory at the University of Lausanne, Switzerland. The primary mission of the laboratory is to transfer adjuvants and formulation technology free of intellectual property rights to academic institutions, small biotechnology companies and developing countries vaccine manufacturers. In this context, the transfer of an oil-in-water emulsion to Bio Farma, an Indonesian vaccine manufacturer, was initiated to increase domestic pandemic influenza vaccine production capacity as part of the national pandemic influenza preparedness plan.
Mots-clé
Adjuvants, Immunologic/administration & dosage, Chemistry, Pharmaceutical/methods, Humans, Switzerland, Technology Transfer, Technology, Pharmaceutical/economics, Technology, Pharmaceutical/legislation & jurisprudence, Vaccines/chemistry, Vaccines/immunology, World Health Organization
Pubmed
Web of science
Open Access
Oui
Création de la notice
27/10/2011 14:07
Dernière modification de la notice
20/08/2019 15:29
Données d'usage