Pyroptosis: Caspase-11 Unlocks the Gates of Death.

Details

Serval ID
serval:BIB_6E958EED3865
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Title
Pyroptosis: Caspase-11 Unlocks the Gates of Death.
Journal
Immunity
Author(s)
de Gassart A., Martinon F.
ISSN
1097-4180 (Electronic)
ISSN-L
1074-7613
Publication state
Published
Issued date
2015
Volume
43
Number
5
Pages
835-837
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
How inflammatory caspases trigger pyroptotic cell death is mostly unexplained. In this issue of Immunity, Núñez and colleagues report that caspase-11 cleaves the transmembrane channel pannexin-1, causing an efflux of cellular ATP that promotes a P2X7 receptor-dependent pyroptosis.
Pubmed
Web of science
Open Access
Yes
Create date
07/12/2015 12:06
Last modification date
20/08/2019 15:27
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