Respiratory effects of an exposure to grain dust among grain workers in the Vaud region (Switzerland)

Details

Serval ID
serval:BIB_6E8506F84FE9
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Title
Respiratory effects of an exposure to grain dust among grain workers in the Vaud region (Switzerland)
Title of the conference
ERS 23rd Annual Congress, Barcelona Spain, 7-11 September 2013
Author(s)
Dorribo Victor, Pralong Jacques A., Wild Pascal, Reboux Gabriel, Oppliger Anne, Danuser Brigitta, Niculita-Hirzel Hélène, Krief Peggy
ISSN-L
1399-3003
Publication state
Published
Issued date
2013
Volume
42
Series
European Respiratory Journal
Pages
201s-202s
Language
english
Abstract
Introduction: Bioaerosols such as grain dust (GD) elicit direct immunological reactions within the human respiratory system. Workplace-dependent exposure to GD may induce asthma, chronic bronchitis, and hypersensitivity pneumonitis.
Aims: To assess the clinical impact of occupational exposure to GD and to determine quantitative biological markers of bioaerosol exposure in grain workers.
Methods: This longitudinal study has been conducted from summer 2012 to summer 2013, comprising 6 groups of 30 active workers with different GD exposure patterns (4 groups of grain workers, 2 control groups). Two evaluations at high- and low-exposing seasons take place, during which an occupational and a medical history are questionnaire-assessed, lung function is evaluated by spirometry, airway inflammation is measured by exhaled nitric oxide (eNO) and specific blood IgG and IgE are titrated.
Results: The preliminary results are those of 2 of the 4 exposed groups, (harvesters and mill workers), compared to the control groups, at first assessment (n=100). Mean age is 38.4 [years]; 98% are male. Exposed groups differ from controls (p<0.05) in daily contact with animals (57% vs. 40%) and active smoking (39% vs. 11%). Grain workers have more respiratory (50%), nasal (57%), ocular (45%) and dermatologic (36%) occupational symptoms than controls (6.4%, 19%, 16%, 6.4% respectively, p<0.05). Lower mean peak-expiratory-flow (PEF) values (96.1 ± 18.9 vs. 108.2 ± 17.4 [% of predicted], p<0.05) and eNO values (13.9 ± 9.6 vs. 20.5 ± 14.7 [ppm], p<0.05) are observed in the exposed groups.
Conclusion: Preliminary results show a higher prevalence of clinical symptoms and a lower mean PEF value in the groups exposed to GD.
Keywords
Occupational Exposure, Endotoxins/analysis, Agricultural Workers' Diseases/prevention & control, Switzerland
Create date
15/10/2013 16:15
Last modification date
20/08/2019 15:27
Usage data