Pneumopathie interstitielle granulomato-lymphocytaire dans l'immunodéficience commune variable [Granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency].

Details

Serval ID
serval:BIB_6BC47993F101
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Pneumopathie interstitielle granulomato-lymphocytaire dans l'immunodéficience commune variable [Granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency].
Journal
Revue Médicale Suisse
Author(s)
Bianchi M.P., Letovanec I., Spertini F., Nicod L.P., Lazor R.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
407
Pages
2175-2180
Language
french
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Abstract
Common variable immunodeficiency (CVID) is the most frequent primary immune deficiency. Recurrent infections are classical consequences of CVID, but their impact has been largely reduced by immunoglobulin replacement. CVID is also associated with various inflammatory and autoimmune manifestations resulting from abnormal cellular immunity. The lungs are especially affected by a recently described entity called granulomatous lymphocytic interstitial lung disease (GLILD). GLILD currently constitutes an important cause of morbidity and mortality in these patients. It is distinct from bronchiectasis secondary to recurrent infections, and presents similarities but also striking differences with sarcoidosis.
Keywords
Bronchiectasis/diagnosis, Bronchiectasis/physiopathology, Common Variable Immunodeficiency/diagnosis, Common Variable Immunodeficiency/physiopathology, Granuloma/diagnosis, Granuloma/pathology, Humans, Immunoglobulins/administration & dosage, Lung Diseases, Interstitial/diagnosis, Lung Diseases, Interstitial/physiopathology, Prognosis, Recurrence, Sarcoidosis/diagnosis, Sarcoidosis/physiopathology
Pubmed
Create date
31/03/2014 16:15
Last modification date
20/08/2019 14:25
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