Circulating sodium in acute meningitis

Details

Serval ID
serval:BIB_6AE76293328C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Circulating sodium in acute meningitis
Journal
American Journal of Nephrology
Author(s)
von Vigier  R. O., Colombo  S. M., Stoffel  P. B., Meregalli  P., Truttmann  A. C., Bianchetti  M. G.
ISSN
0250-8095 (Print)
Publication state
Published
Issued date
04/2001
Volume
21
Number
2
Pages
87-90
Notes
Journal Article --- Old month value: Mar-Apr
Abstract
BACKGROUND: In acute meningitis hyponatremia is common and traditionally attributed exclusively to inappropriate water retention. However, the exact mechanisms underlying hyponatremia are unknown. METHODS: The files of 300 pediatric patients with acute bacterial (n = 190) or aseptic (n = 110) meningitides were retrospectively analyzed. RESULTS: The plasma sodium level ranged from 122 to 148 mmol/l and was low (<133 mmol/l) in 97 patients. Fluid volume contraction was significantly more pronounced in hyponatremia (median 6.0. 10(-2)) than in normonatremia (median 2.0. 10(-2)). The fractional sodium excretion was less than 1.00. 10(-2) in the 26 hyponatremic children with this measurement. CONCLUSION: In acute meningitis hyponatremia is not exclusively brought about by inappropriate water retention.
Keywords
Acute Disease Female Humans Hyponatremia/etiology Infant Infant, Newborn Male Meningitis/*blood/complications Meningitis, Aseptic/blood/complications Meningitis, Bacterial/blood/complications Retrospective Studies Sodium/*blood
Pubmed
Web of science
Create date
28/01/2008 13:50
Last modification date
20/08/2019 14:25
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