Selective activation of ectopic grey matter during motor task.

Details

Serval ID
serval:BIB_65A30D1F3F01
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Selective activation of ectopic grey matter during motor task.
Journal
Neuroreport
Author(s)
Draganski B., Winkler J., Flügel D., May A.
ISSN
0959-4965 (Print)
ISSN-L
0959-4965
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
15
Number
2
Pages
251-253
Language
english
Notes
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
Abstract
The role of ectopic grey matter in neuronal migration disorders is still a matter of debate. Using fMRI we studied the activation pattern of ectopic and regular cortical neurons in a female patient with subcortical bilateral laminar heterotopia (double cortex syndrome) performing a simple motor task. We demonstrate a synchronous activation pattern of the motor cortex and the adjacent subcortical ectopic grey matter layer during finger-tapping. We also observed activation in the cerebellum ipsilaterally and in the basal ganglia contralaterally. The present findings are consistent with the hypothesis that ectopic neurons may be functionally integrated in motor circuits during repetitive voluntary movements.
Keywords
Adult, Basal Ganglia/anatomy & histology, Basal Ganglia/physiology, Brain Mapping, Cell Movement/physiology, Cerebellum/anatomy & histology, Cerebellum/physiology, Cerebral Cortex/abnormalities, Cerebral Cortex/physiology, Choristoma/pathology, Choristoma/physiopathology, Electroencephalography, Female, Functional Laterality/physiology, Humans, Magnetic Resonance Imaging, Motor Cortex/anatomy & histology, Motor Cortex/physiology, Movement/physiology, Nervous System Malformations/pathology, Nervous System Malformations/physiopathology, Neural Pathways/anatomy & histology, Neural Pathways/physiology, Psychomotor Performance/physiology
Pubmed
Web of science
Create date
18/01/2013 17:57
Last modification date
20/08/2019 14:21
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