Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Selective activation of ectopic grey matter during motor task.
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
The role of ectopic grey matter in neuronal migration disorders is still a matter of debate. Using fMRI we studied the activation pattern of ectopic and regular cortical neurons in a female patient with subcortical bilateral laminar heterotopia (double cortex syndrome) performing a simple motor task. We demonstrate a synchronous activation pattern of the motor cortex and the adjacent subcortical ectopic grey matter layer during finger-tapping. We also observed activation in the cerebellum ipsilaterally and in the basal ganglia contralaterally. The present findings are consistent with the hypothesis that ectopic neurons may be functionally integrated in motor circuits during repetitive voluntary movements.
Adult, Basal Ganglia/anatomy & histology, Basal Ganglia/physiology, Brain Mapping, Cell Movement/physiology, Cerebellum/anatomy & histology, Cerebellum/physiology, Cerebral Cortex/abnormalities, Cerebral Cortex/physiology, Choristoma/pathology, Choristoma/physiopathology, Electroencephalography, Female, Functional Laterality/physiology, Humans, Magnetic Resonance Imaging, Motor Cortex/anatomy & histology, Motor Cortex/physiology, Movement/physiology, Nervous System Malformations/pathology, Nervous System Malformations/physiopathology, Neural Pathways/anatomy & histology, Neural Pathways/physiology, Psychomotor Performance/physiology
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