An ontology to clarify homology-related concepts.

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Serval ID
serval:BIB_611EAEEC4DD5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
An ontology to clarify homology-related concepts.
Journal
Trends in Genetics
Author(s)
Roux J., Robinson-Rechavi M.
ISSN
0168-9525 (Print)
ISSN-L
0168-9525
Publication state
Published
Issued date
2010
Peer-reviewed
Oui
Volume
26
Number
3
Pages
99-102
Language
english
Abstract
Although homology is a fundamental concept in biology and is one of the shared channels of communication universal to all biology, it is difficult to find a consensus definition. Indeed, the interpretations of homology have changed as biology has progressed. New terms, such as paramorphism, have been introduced into the literature with mixed success. In addition, different research fields operate with different definitions of homology, for example the mechanistic usage of evo-devo is not strictly historical and would not be acceptable in cladistics. This makes a global understanding of homology complex, whereas the integration of evolutionary concepts into bioinformatics and genomics is increasingly important. We propose an ontology organizing homology and related concepts and hope this solution will also facilitate the integration and sharing of knowledge among the community.
Keywords
Animals, Biological Evolution, Computational Biology, Humans, Models, Genetic
Pubmed
Web of science
Open Access
Yes
Create date
04/01/2010 11:34
Last modification date
20/08/2019 15:18
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