[Excess mortality and sudden unexpected death in epilepsy]

Details

Serval ID
serval:BIB_610DDCB053AA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
[Excess mortality and sudden unexpected death in epilepsy]
Journal
Presse Med
Author(s)
Ryvlin P., Tomson T., Montavont A.
ISSN
2213-0276 (Electronic)
ISSN-L
0755-4982
Publication state
Published
Issued date
06/2009
Volume
38
Number
6
Pages
905-10
Language
french
Notes
Ryvlin, Philippe
Tomson, Torbjorn
Montavont, Alexandra
fre
English Abstract
Review
France
Presse Med. 2009 Jun;38(6):905-10. doi: 10.1016/j.lpm.2008.12.009. Epub 2009 Jan 25.
Abstract
Patients with epilepsy have a two to three fold increased risk of death as compared to the age-matched general population. This increased risk of death primarily affects young adults with drug resistant epilepsy. Sudden unexpected death in epilepsy (SUDEP) is one of the main cause of mortality in that population, and appears to be the direct consequence of a seizure. The pathophysiology of SUDEP remains unclear, but a post-ictal central or obstructive apnea seems to represent the most likely mechanism. The risk of SUDEP is increased in patients with nocturnal seizures, generalized tonic-clonic seizures, and poor compliance. This risk can be decreased by nocturnal supervision. There is yet no consensus regarding the information about SUDEP that should be delivered to patients with epilepsy, but it seems reasonable to individualize this information according to each patient form of epilepsy.
Keywords
Age Distribution, Anticonvulsants/therapeutic use, *Cause of Death, *Death, Sudden/epidemiology/etiology/prevention & control, Drug Resistance, Electrocardiography, Electroencephalography, Epilepsy/*complications/diagnosis/*mortality/therapy, Epilepsy, Tonic-Clonic/complications, Europe/epidemiology, France/epidemiology, Health Services Needs and Demand, Humans, Medication Adherence, Night Care, Risk Assessment, Risk Factors, Sleep Apnea, Central/etiology, Sleep Apnea, Obstructive/etiology, Time Factors
Pubmed
Create date
29/11/2018 12:37
Last modification date
20/08/2019 14:18
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