[Excess mortality and sudden unexpected death in epilepsy]

Détails

ID Serval
serval:BIB_610DDCB053AA
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
[Excess mortality and sudden unexpected death in epilepsy]
Périodique
Presse Med
Auteur⸱e⸱s
Ryvlin P., Tomson T., Montavont A.
ISSN
2213-0276 (Electronic)
ISSN-L
0755-4982
Statut éditorial
Publié
Date de publication
06/2009
Volume
38
Numéro
6
Pages
905-10
Langue
français
Notes
Ryvlin, Philippe
Tomson, Torbjorn
Montavont, Alexandra
fre
English Abstract
Review
France
Presse Med. 2009 Jun;38(6):905-10. doi: 10.1016/j.lpm.2008.12.009. Epub 2009 Jan 25.
Résumé
Patients with epilepsy have a two to three fold increased risk of death as compared to the age-matched general population. This increased risk of death primarily affects young adults with drug resistant epilepsy. Sudden unexpected death in epilepsy (SUDEP) is one of the main cause of mortality in that population, and appears to be the direct consequence of a seizure. The pathophysiology of SUDEP remains unclear, but a post-ictal central or obstructive apnea seems to represent the most likely mechanism. The risk of SUDEP is increased in patients with nocturnal seizures, generalized tonic-clonic seizures, and poor compliance. This risk can be decreased by nocturnal supervision. There is yet no consensus regarding the information about SUDEP that should be delivered to patients with epilepsy, but it seems reasonable to individualize this information according to each patient form of epilepsy.
Mots-clé
Age Distribution, Anticonvulsants/therapeutic use, *Cause of Death, *Death, Sudden/epidemiology/etiology/prevention & control, Drug Resistance, Electrocardiography, Electroencephalography, Epilepsy/*complications/diagnosis/*mortality/therapy, Epilepsy, Tonic-Clonic/complications, Europe/epidemiology, France/epidemiology, Health Services Needs and Demand, Humans, Medication Adherence, Night Care, Risk Assessment, Risk Factors, Sleep Apnea, Central/etiology, Sleep Apnea, Obstructive/etiology, Time Factors
Pubmed
Création de la notice
29/11/2018 13:37
Dernière modification de la notice
20/08/2019 15:18
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