Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI
Details
Serval ID
serval:BIB_5C5324AFB13F
Type
Inproceedings: an article in a conference proceedings.
Collection
Publications
Institution
Title
Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI
Title of the conference
22nd annual meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Publication state
Published
Issued date
2014
Notes
EPFL-CONF-211189
Abstract
Conventional magnetic resonance imaging (MRI) measures
of multiple sclerosis patients provide limited
information about the nature and the extent of brain
damage and repair. We established a clinically compatible
protocol including quantitative MRI techniques (qMRI, T1,
T2, T2* relaxometry) and semiquantitative Magnetisation
Transfer Imaging to provide a comprehensive MRI
fingerprint (CMF) of lesions that is more adherent to the
real underlying pathology and to assess the CMF
contribution to clinical performances in patients.
Lesions characteristics, revealed by combination of q/sq
MRI, highly correlated with patients clinical performance
and more severe lesions appeared to drive the
clinic-radiological correlations.
of multiple sclerosis patients provide limited
information about the nature and the extent of brain
damage and repair. We established a clinically compatible
protocol including quantitative MRI techniques (qMRI, T1,
T2, T2* relaxometry) and semiquantitative Magnetisation
Transfer Imaging to provide a comprehensive MRI
fingerprint (CMF) of lesions that is more adherent to the
real underlying pathology and to assess the CMF
contribution to clinical performances in patients.
Lesions characteristics, revealed by combination of q/sq
MRI, highly correlated with patients clinical performance
and more severe lesions appeared to drive the
clinic-radiological correlations.
Create date
27/11/2015 14:14
Last modification date
21/08/2019 5:36
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